How Much Do Puppy Shots Cost at PetSmart?

How Much Do Puppy Shots Cost at PetSmart?

Owning a puppy is one of life’s most rewarding experiences, but it also comes with responsibilities that require careful financial planning. Beyond daily needs like nutritious food, tasty treats, grooming tools, engaging toys, pee pads, collars, leashes, and deworming medication, one of the most critical early investments is vaccination. Core puppy vaccines protect against potentially deadly illnesses such as rabies, canine distemper, bordetella bronchiseptica, leptospirosis, canine parvovirus, and canine influenza.

Early vaccinations are essential for building a strong immune system, lowering the risk of serious disease, and supporting long-term health. Because many new pet owners are concerned about how much puppy shots cost, it’s important to explore affordable, accessible care options — whether through a traditional veterinarian, a local pet store, or a walk-in veterinary clinic.

If you’re specifically wondering how much puppy shots cost at PetSmart, the answer depends on which in-store veterinary partner you choose and the location of your visit. PetSmart does not administer vaccines directly, but many locations partner with providers like Banfield Pet Hospital, ShotVet, and other independent veterinary medicine operators. These in-store partners offer convenient access to vaccination packages designed to cover the core set of puppy immunizations.

Getting Puppy Vaccine Shots at PetSmart

PetSmart is a popular choice among pet owners concerned about the cost of vaccines. While PetSmart stores do not administer vaccinations themselves, many locations host in-store veterinary partners like Banfield Pet Hospital, ShotVet, and other independent veterinary medicine providers. These providers offer convenient access to puppy vaccine packages that include the core set of immunizations.

Key vaccines commonly administered through these providers include:

• Rabies vaccine – A legally required dose in most states to protect both pets and humans from this deadly virus
• Canine distemper – An essential vaccine against a highly contagious viral disease
• Bordetella – Recommended to prevent kennel cough, especially for puppies that may be boarded or groomed
• Leptospirosis – Guards against a bacterial disease that affects the kidneys and liver
• Canine parvovirus – A critical vaccine to prevent life-threatening gastrointestinal illness in puppies

Similarly, you can find on the PetSmart website that they list Banfield Pet Hospital, ShotVet, and independent vet operators, as available veterinarians in their PetSmart locations, offering packages at competitive prices. This way, you can ensure your puppy receives the necessary vaccines from any location near you. 

Puppy Shots & Services Cost- Banfield Hospital

If you opt for Banfield Hospital for your puppy’s vaccinations, the cost will vary depending on the location. To get a rough estimate, you can use their online Price Estimator, which provides a breakdown of the cost of each shot. 

If you are in Illinois, estimated individual price costs are as follows: 

On the other hand, you also have the option to get their Optimum Wellness Plan, which is a package plan for preventive pet care services. You have the option to pay these on a monthly or yearly basis with no interest charge: 

For Puppies Below Six Months

For Dogs Above Six Months 

Puppy Shots & Services Cost- ShotVet

When choosing ShotVet for your puppy’s vaccinations, you can get a rough estimate by answering their online Quiz to help you determine your dog’s needs. Once you have chosen the individual shots or vaccine packages you would like for your pup, you will be routed to set up an appointment. Here is the cost of their packages as posted online:

Puppies

Adult Dogs

What Are The Additional Costs?

While the prices of vaccines and packages are available online, the only way to know if there will be any possible costs is after a veterinarian has checked your puppy and conducted tests and bloodwork. Upon checkup, a good vet will be able to determine if your dog has any possible underlying conditions and what shots he would benefit from getting.

Aside from this, there shouldn’t be any additional costs apart from the puppy shots or shot packages that you chose.

How Often Should My Puppy Get Vaccinated?

During their first year, puppies receive their vaccines from six weeks until they are sixteen weeks old. During this time, getting their vaccines is crucial, as it ensures they are protected from diseases while helping to build up their immune system. After the first year, your pup will receive their annual vaccines to ensure they remain continuously protected.

Check out our vaccine shots guide here.

Can I Bring My Puppy Outside Without Getting Vaccinated?

Puppies still have developing immune systems and are very susceptible to diseases and viruses outdoors and from other animals they may encounter. When you bring your pup outdoors before completing its vaccines, the chances of getting fatal diseases are very high.

Read: When Can I Take My Puppy to the Dog Park?

If you are going on a trip and would like to bring your pup, consult your veterinarian to determine whether it will be safe. Otherwise, having a friend, relative, or puppy boarding service take care of your furry pal would be best. For puppy boarding, contact us at Happy Pup Manor today. We have expert trainers in a home setting where your pup will be welcomed and embraced with love and care!

Keep Reading: What Shots Does My Puppy Need? 

Frequently Asked Questions

Do puppy vaccines need to be given in a specific order?
Yes. Core vaccines are typically administered in a series that starts with combination shots for diseases like distemper and parvovirus, followed by boosters and additional non-core vaccines. Your vet will create a schedule based on your puppy’s age, health, and risk factors.

What should I bring when taking my puppy for vaccinations?
Bring your puppy’s medical history, any previous vaccination records, and a list of current medications or supplements. If this is your puppy’s first vet visit, include breeder or shelter paperwork for reference.

Are there side effects after puppy vaccinations?
Most puppies experience only mild side effects like slight soreness at the injection site, mild lethargy, or a small decrease in appetite. Serious reactions are rare, but contact your vet immediately if you notice persistent vomiting, swelling, or difficulty breathing.

Can I combine my puppy’s vaccines with other vet services to save money?
Many providers, including those at PetSmart partner clinics, offer bundled services such as wellness exams, microchipping, or parasite prevention alongside vaccinations. Ask if combining services can reduce overall costs.

How do I prepare my puppy for their first vaccination appointment?
Help your puppy feel comfortable with handling by gently touching their paws, ears, and mouth in the days leading up to the appointment. Bring a favorite toy or blanket for comfort and ensure they’ve had a chance to relieve themselves before going inside.

Is it safe to socialize my puppy before all shots are completed?
While full outdoor exposure should wait until the vaccine series is complete, controlled socialization with healthy, vaccinated dogs in safe environments can help with behavioral development. Your vet can advise on safe settings for early interaction.